Researchers at Duke University have made a significant advancement in understanding OCD, as they announced last Friday that they have identified a receptor in the brain that may cause the disorder. Though their research was originally conducted in mice, it opens doors for the development of new more targeted and likely more effective medications and treatments ...
"When comparing regular mice to mice that lacked the Sapap3 gene, researchers discovered that the mice without it often had an overactive direct pathway, seemingly explaining why they are so prone to repeating the same actions over and over. When scientists did even more digging, they realize that a specific chemical receptor, called mGluR5, was consistently active in the brains of the mice who lacked Sapap3. This finding suggests that mGluR5 may control the hyperactivity of the brain circuits that coordinate action, thus possibly explaining why so many people with OCD have both obsessive thoughts and obsessive actions."
To read more about the study click here:
http://www.bustle.com/…/173805-what-causes-ocd-scientists-m…
http://thescienceexplorer.com/…/researchers-find-switch-ocd…
For the original abstract click here:
http://www.biologicalpsychiatryjournal.com/…/S0006…/abstract
"When comparing regular mice to mice that lacked the Sapap3 gene, researchers discovered that the mice without it often had an overactive direct pathway, seemingly explaining why they are so prone to repeating the same actions over and over. When scientists did even more digging, they realize that a specific chemical receptor, called mGluR5, was consistently active in the brains of the mice who lacked Sapap3. This finding suggests that mGluR5 may control the hyperactivity of the brain circuits that coordinate action, thus possibly explaining why so many people with OCD have both obsessive thoughts and obsessive actions."
To read more about the study click here:
http://www.bustle.com/…/173805-what-causes-ocd-scientists-m…
http://thescienceexplorer.com/…/researchers-find-switch-ocd…
For the original abstract click here:
http://www.biologicalpsychiatryjournal.com/…/S0006…/abstract
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