Brains of volunteers on LSD become less organised and more chaotic. Dr Carhart-Harris believes that hallucinogens may temporally "loosen" the rigid structures of the brain. “An acid trip is a bit like shaking up a snow globe. This loosening could help the brain break the cycles of addiction and depression.”
Like LSD, magic mushrooms are also hallucinogenic. A study showed that the compound helps suppress the part of the brain often hyperactive in depression. Psilocybin, the active compound in magic mushrooms may also be useful in treating addiction. A study by John Hopkins University gave 15 people trying to give up smoking two to three rounds of the psilobin. Six months later, 12 remained off cigarettes – a success rate of 80%. The best smoking cessation drugs are 35% effective. While promising, a much bigger study is needed.
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